10 scientific reasons why you feel depressed (2023)

10 scientific reasons why you feel depressed (1)

Fuente: Aleshyn_Andrei/Shuttersock

Do you wake up most days feeling "blah"? Maybe you don't want to do anything more than sit around like a couch potato and watch TV, and even that is unsatisfying. “You're mad at yourself for not being able to clean the house, or do your work, or file papers. Perhaps you feel a little lonely, left out by friends or without the support of family. 10 or 20 pounds overweight. He may experience neck or back pain. Or you may be feeling grumpy and want to remain unfazed by life's demands and opportunities for conversation. You may compare yourself unfavorably to your friend, roommate, cousin, or neighbor, who always seems to be on time, well-groomed, and on track to accomplish his goals. We all have those "blah" days, but why do they happen and what can we do? Do This Below are 10 scientific reasons why you might feel sick.

(Video) 8 Reasons Why You Feel Depressed

brain chemicals

Some of us have brains that are more sensitive to the effects of stress. Researchers are just beginning to uncover the biochemistry behind this differential. The most common forms ofantidepressantstarget the neurotransmitters serotonin and norepinephrine because some research concludes that low levels of these chemical motivators are part of what gets us down. However, only a few people respond well to the most common forms of antidepressants, while others try one drug after another without substantial mood improvement. A recent research study, published earlier this year inAnnals of the National Academy of Sciences,can reveal the reason. Research suggests that differences in the way our brains process a chemical called galanin may make some of us lessresilientand able to recover after difficult experiences.

The weather

Less sun during the winter months can make us sad, and this effect is more pronounced for some people than others. researcherskeller and colleaguesHe studied hundreds of people and discovered that during the spring the mood improved; participants also reported more outdoor activities. We may also be more cognitively flexible and able to think creatively about how to solve our problems in spring compared to winter. A subgroup of people suffer from Seasonal Affective Disorder, a condition in which the winter blues become completelydepressionalong with associated changes in sleep,appetite, mimotivation. Victims are more likely to be women. Exposure to outdoor sunlight also provides us with vitamin D, a substance with clear links to depressed mood.

Vitamin D

Most people in the US have insufficient or deficient levels ofVitamin D.The reasons are not clear, but may be related.nutritionand insufficient sun exposure. People with dark skin are more vulnerable to vitamin D deficiency due to their decreased ability to process vitamin D from sunlight. Vitamin D deficiency has been statistically linked to depression. In a large Dutch study ofHoogendijk and colleagues (2008) of more than 1,200 people age 65 and older, vitamin D levels were 14% lower in people with major or minor depressive disorder compared with those without depressed mood.


Hormones are substances produced by theendocrineglands that influence many bodily functions, including growth and development, mood,sexualFunction and metabolism. The levels of certain hormones, such as those produced by thethyroid gland, may be factors of depression. Additionally, some symptoms of depression are associated with thyroid conditions. Hormones fluctuate during the menstrual cycle and can create vulnerability to sad or depressed moods both before and during pregnancy.perimenopauseand menopause. There are individual differences in the vulnerability of our moods to the effects of hormones. If you are more vulnerable, you may want to see a doctor to see if medication is needed to help regulate your hormones. you can also tryalternative medicinetreatments, such as acupuncture, to reduce hormone-related mood imbalance.


Our moods are not just a function of what happens to us, but also how we view the events in our lives and the meanings we give them. There are phases in most of our lives where it seems like we're working hard and doing all the right things, but we don't see many external rewards coming our way. We may not be paid what we think we're worth, or we may not be able to afford a house, car, or vacation as nice as our friends'. We may have a hard time finding the right partner, while our friends or siblings seem to have no problem finding love. We may have to work harder and harder than our friends to get the same grade on a test or to earn a living. We may experience a difficult separation or loss. Life, naturally, is not fair; periods of struggle, suffering and loss are inevitable. If we expect fair or special treatment all the time or hope that things will never change, we are bound to be disappointed. So if you are feeling down because of recent events, remember that hard times are a part of life and they will pass. You might also try to deliberately broaden your vision and focus on the good parts of your life or experiences you are proud of.

Adverse events in childhood

stressfulLife events can deplete our physical and mental resources, making us more vulnerable to depression and physical illness.A story of childhood trauma., including abuse, poverty, or the loss of a parent, can reset our developing brains to be less cognitively flexible. It seems that our brains naturally go into a "fight, flight, freeze" response to stress or threat, and we often have to use our prefrontal cortex or executive center to get out of that state. prolonged stress onchildhoodit can make our brains less interconnected and resilient; our brains can more easily "get stuck" onnegative thinkingaccentuated patterns or states, making us less able to change lanes.

(Video) 6 Signs You're Depressed, Not Lazy


  • What is depression?
  • Find a therapist to overcome depression.

stress builds up

As Robert Sapolsky argues in his book,Why don't zebras have ulcers?, our human stress response systems are designed to respond to acute and time-limited stressors that normally require a physical response. When our ancestors were chasing that prowling tiger, they could relax and eat. Stressors in today's world are much more chronic and less capable of being controlled by action, and we often don't have time to recover and reorganize. financial stress,soledad, constant fights with loved ones, bullying, long commutes, academic or job demands, or unemployment can drag on, unleashing a cascade of effects in many areas of our lives. When stress hits us one after another with no time to recover, it can leave us exhausted and despondent, without enough energy to recover.

negative ruminations

You may be feeling depressed because you are sitting around thinking about life's disappointments or trying to find a reason why things are not going your way. Research Studies by Psychologists at the University of MichiganSusan Nolen-Hoeksema and colleaguesPoint out that sitting around thinking about your negative mood or negative events only makes it worse. One negative thought leads to another, and then another, until it is buried under a mountain of negative problems and predictions. This can easily lead to a loss of perspective and motivation, which can interfere with taking action to resolve the problem. If you find yourself in a negative thought cycle, get up immediately and do something pleasant or neutral to occupy your mind. This could be as simple as emptying the dishwasher, rearranging your closet, going for a walk, catching up with a friend, or starting a work project.

Essential reading on depression

The worst way to think about happiness and sadness.

(Video) How Depression Affects The Brain - Yale Medicine Explains

How feeling unloved as a child can lead to depression as an adult

(Video) This could be why you're depressed or anxious | Johann Hari

your inner critic

Do you have a critical inner voice that is constantly judging and criticizing everything you do, especially when things don't go your way? EITHERinner criticexacerbate the effect of anything negative in your life by blaming yourself for it. Continue drawing yourattentionto the negative and spoil your pleasure when something positive happens by telling yourself "it won't last" or "you don't deserve it." This negative dialogue takes you out of the moment and gets you down.negative thinkingit can be a symptom of depression and can be a causal factor in interaction with negative life events.

The first step in combating an internal critic is to realize what they are saying; the second step is to outsource it. You might name your critic and imagine what he looks like, picturing him as a grumpy old woman, for example, or a ferociously barking dog. Then start talking back and tell him to back off. The inner critic often has a negative outlook and overestimates his responsibility and control over the outcomes of her life. He also usually hasperfectionistExpectations. Tell him to give you a break for a change!


Our human brains are wired to be part of a social group, and we experiencesoledadas chronically stressful and depressing. Sadly, some of us have toxic or neglectful families that don't provide support or presence when we need it. In the same way, we can feel that our friends are moving on, findingromantic relationshipsor have children, for example - and leave us behind. Research using fMRI brain scans shows that even the slightest social rejection turns on the same areas of our brains that physical pain does. Feeling excluded, rejected or left out makes us sad; It can also lead to reflect on our faults, further worsening our state of mind. We become scared of further rejection and isolate ourselves, perpetuating the negative cycle. While there may not be an immediate cure for loneliness, it helps to get out into the world and pursue your natural interests, which can lead to expanding yourred social. Keeping in touch with old friends or family and deliberately looking for opportunities to connect can also help.

final thoughts

The reasons for a depressed mood are often multifaceted and can be difficult to determine. If you feel depressed for two weeks or more, see a doctor to rule out or treat underlying biological factors. Consider seeing a mental health professional to help you manage stress and expectations, negotiate life changes, or deal with emotional fallout from the past.traumasand dysfunctional families. if you can't paytherapy, antidepressants can still help change the underlying biology. Exercising outdoors can provide sunlight and lift your spirits. Develop a toolkit of stress-reducing activities, such as regular exercise, yoga, ormeditation, watch funny movies, play team sports, do something creative or innovative, and go out and/or confide in supportive friends.

(Video) Why Do You Feel Sad for No Reason Sometimes?

To find a therapist, visit theDirectory of Psychological Therapy Today.


What are 10 major causes of depression? ›

What causes depression?
  • Childhood experiences.
  • Life events.
  • Styles of thinking.
  • Other mental health problems.
  • Physical health problems.
  • Family history.
  • Medication.
  • Recreational drugs and alcohol.

Is there a scientific reason for depression? ›

Research suggests that depression doesn't spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events.

What are 5 causes of depression? ›

Causes - Clinical depression
  • Stressful events. Most people take time to come to terms with stressful events, such as bereavement or a relationship breakdown. ...
  • Personality. ...
  • Family history. ...
  • Giving birth. ...
  • Loneliness. ...
  • Alcohol and drugs. ...
  • Illness.

What are the 12 signs of depression? ›

12 Signs of Depression
  • Fatigue. ...
  • Sleep Disturbance. ...
  • Cognitive Dysfunction or Difficulty Concentrating. ...
  • Feelings of Worthlessness or Hopelessness. ...
  • Irritability or Restlessness. ...
  • Loss of Interest in Hobbies or Activities. ...
  • Appetite Changes. ...
  • Persistent Aches or Pains.
May 15, 2018

What are the 10 hits of depression? ›

The 10 hit categories are the following: (1) genetic, (2) developmental, (3) lifestyle, (4) circadian rhythm, (5) addiction, (6) nutrition, (7) toxic, (8) social/complicated grief, (9) medical condition, and (10) frontal lobe.

What are the 4 major types of depression? ›

Types of major depression include melancholia, psychotic and antenatal or postnatal. You may be diagnosed with mild, moderate or severe depression. Your mental health professional may diagnose you with depression if these symptoms: happen most days.

What is a depression in science terms? ›

Scientific definitions for depression

A region of low atmospheric pressure. Low pressure systems result in precipitation, ranging from mild to severe in intensity. See also cyclone.

What happens in the brain during depression? ›

Depression causes the hippocampus to raise its cortisol levels, impeding the development of neurons in your brain. The shrinkage of brain circuits is closely connected to the reduction of the affected part's function. While other cerebral areas shrink due to high levels of cortisol, the amygdala enlarges.

What is depression scientifically in the brain? ›

Depression involves an overemphasis of negative emotions and a decrease in the reward produced by pleasurable experiences. Chronic stress can be important in the development of depression. An inability to cope with stress causes changes in how the brain balances positive and negative information.

What is the highest cause of depression? ›

Depression results from a complex interaction of social, psychological, and biological factors. People who have gone through adverse life events (unemployment, bereavement, traumatic events) are more likely to develop depression.

What is the most common factor of depression? ›

Risk Factors
  • Genetics: A history of depression in your family may make it more likely for you to get it. ...
  • Death or loss: Sadness and grief are normal reactions. ...
  • Conflict: Personal turmoil or disputes with family or friends may lead to depression.
  • Abuse: Past physical, sexual, or emotional abuse can bring it on, as well.

What are the Big Five and depression? ›

Four of the Big Five personality traits (conscientiousness, extraversion, agreeableness and neuroticism) were associated with depression scores.

What are the 7 forms of depression? ›

7 Common Types of Depression
  • Major Depressive Disorder (MDD) ...
  • Persistent Depressive Disorder (PDD) ...
  • Bipolar Disorder. ...
  • Postpartum Depression (PPD) ...
  • Premenstrual Dysphoric Disorder (PMDD) ...
  • Seasonal Affective Disorder (SAD) ...
  • Atypical Depression.

When does depression kick in? ›

Young Adults. Young adults ages 19 to 29 sometimes develop depression due to major life transitions, lack of support in new environments, lack of coping skills, relationship issues, poverty, trauma, work issues and more.

What are 3 symptoms of big depression? ›

Feelings of sadness, tearfulness, emptiness or hopelessness. Angry outbursts, irritability or frustration, even over small matters. Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports. Sleep disturbances, including insomnia or sleeping too much.

What are the 5 categories of depression? ›

Types of Depression
  • Psychotic Depression.
  • Seasonal Affective Disorder.
  • Persistent Depressive Disorder.
  • Postpartum Depression.

How devastating is depression? ›

Such depression interferes with your daily life and relationships. But some cases of depression are more severe, with intense symptoms that may include significant appetite and weight loss, sleep problems, and frequent thoughts of death or suicide. Such depression can be paralyzing.

What are the parts of depression? ›

Major Depression
  • Loss of interest or pleasure in your activities.
  • Weight loss or gain.
  • Trouble getting to sleep or feeling sleepy during the day.
  • Feeling restless and agitated, or else very sluggish and slowed down physically or mentally.
  • Being tired and without energy.
  • Feeling worthless or guilty.
Jun 23, 2021

What is the hardest type of depression? ›

Clinical depression is the more-severe form of depression, also known as major depression or major depressive disorder. It isn't the same as depression caused by a loss, such as the death of a loved one, or a medical condition, such as a thyroid disorder.

What is stage 2 depression? ›

Stage 2: Establishment

This is the stage where depression starts to settle in and become the norm. Sadness, apathy, and general lack of interest may start to become the norm. You might start to feel less interest in things that you used to take great pleasure in.

How long do depressive episodes last? ›

So how long do depressive episodes last? Usually, the depressive episode length ranges from six months to eight months, depending on the person. While some people may have depression that fades, others may struggle with depression on and off their whole life.

What is water depression? ›

Dehydration also depletes the levels of other amino acids in your brain, leading to feelings of anxiety, dejection, irritability, and inadequacy. The third most common way dehydration can lead to depression is by increasing stress in your body.

Which is not a symptom of depression? ›

Bipolar disorder

During a depressed period, you may feel sadness, hopelessness, and loss of interest in activities. But then it will switch to a period of mania, when you feel euphoric, energetic, or irritable. Those are not symptoms of clinical depression.

Is depression curable or just treatable? ›

There's no cure for depression, but you still have plenty of options for treatment, all of which can improve your symptoms and minimize their impact on your daily life.

Can the brain heal from depression? ›

Dendrites are cellular extensions found in the neurons, or nerve cells. This suggests that depression is not an irreversible neurodegenerative disorder. Instead, its impact on the brain may be reversible, and the brain can heal.

What part of the brain is damaged in depression? ›

The main subcortical limbic brain regions implicated in depression are the amygdala, hippocampus, and the dorsomedial thalamus. Both structural and functional abnormalities in these areas have been found in depression.

Is depression a symptom of brain damage? ›

Depression may result from injury to the areas of the brain that control emotions. Changes in the levels of certain natural chemicals in the brain, called neurotransmitters, can cause depression.

What is the sad hormone called? ›

production of serotonin – serotonin is a hormone that affects your mood, appetite and sleep; a lack of sunlight may lead to lower serotonin levels, which is linked to feelings of depression.

What causes low serotonin? ›

Causes of low serotonin

age-related health and brain changes. chronic stress. a lack of exposure to natural light. lack of physical activity.

How does depression affect thinking? ›

Depression affects more than just emotion and mood. It can also change the way your brain functions. The potential cognitive changes from depression include executive dysfunction, impaired learning and memory, reduced attention and concentration, and lower processing speed.

What chemicals are released during depression? ›

People with clinical depression often have increased levels of monoamine oxidase A (MAO-A), an enzyme that breaks down key neurotransmitters, resulting in very low levels of serotonin, dopamine and norepinephrine.

Do most people beat depression? ›

Depression is very treatable. But, only about half of all Americans who are diagnosed with depression in a given year get treatment.

How do I know if my depression is genetic? ›

Depression does not have a clear pattern of inheritance in families. People who have a first-degree relative (for example, a parent or sibling) with depression appear to have a two to three times greater risk of developing the condition than the general public.

What is major depression order? ›

It is diagnosed when an individual has a persistently low or depressed mood, anhedonia or decreased interest in pleasurable activities, feelings of guilt or worthlessness, lack of energy, poor concentration, appetite changes, psychomotor retardation or agitation, sleep disturbances, or suicidal thoughts.

What are the three C's of depression? ›

The Three Cs of Disclosing Serious Mental Illness at Work: Control, Conditions, Costs.

What are the 3 P's of depression? ›

The 3 P's stand for Pervasiveness, Permanence and Personalisation. Pervasiveness looks at how much of your life a concern impacts – How big? Permanence looks at how long an issue is going to be of concern – How long? Personalisation looks at how much you feel you are to blame – How much?

What are 6 causes of depression? ›

Some examples of chronic illnesses that may cause depression are diabetes, heart disease, arthritis, kidney disease, HIV and AIDS, lupus, and multiple sclerosis (MS).

What is the next stage after depression? ›

The five stages are: denial, anger, bargaining, depression, and acceptance.

What is first episode of depression? ›

Share on Pinterest Symptoms of a depressive episode may include anxiety, frustration, feeling hopeless, fatigue, and a loss of interest in things once enjoyed. Symptoms of a depressive episode are more extreme than normal periods of low mood and may include: feeling sad, hopeless, or helpless.

When is the peak of depressive episode? ›

In their lifetime, 20% to 25% of women, and 7% to 12% of men will have a major depressive episode. The peak period of development is between the ages of 25 and 44 years. Onset of major depressive episodes or MDD often occurs to people in their mid-20s, and less often to those over 65.

What does a breakdown feel like? ›

feel isolated — disinterested in the company of family and friends, or withdrawing from usual daily activities. feel overwhelmed — unable to concentrate or make decisions. be moody — feeling low or depression; feeling burnt out; emotional outbursts of uncontrollable anger, fear, helplessness or crying.

What were the 4 major causes of the depression? ›

Among the suggested causes of the Great Depression are: the stock market crash of 1929; the collapse of world trade due to the Smoot-Hawley Tariff; government policies; bank failures and panics; and the collapse of the money supply.

What are signs of anxiety? ›

These can include:
  • a churning feeling in your stomach.
  • feeling light-headed or dizzy.
  • pins and needles.
  • feeling restless or unable to sit still.
  • headaches, backache or other aches and pains.
  • faster breathing.
  • a fast, thumping or irregular heartbeat.
  • sweating or hot flushes.

What might depression lead to? ›

Depression often gets worse if it isn't treated, resulting in emotional, behavioral and health problems that affect every area of your life. Examples of complications associated with depression include: Excess weight or obesity, which can lead to heart disease and diabetes. Pain or physical illness.

What is the most major form of depression? ›

Clinical depression is the more-severe form of depression, also known as major depression or major depressive disorder. It isn't the same as depression caused by a loss, such as the death of a loved one, or a medical condition, such as a thyroid disorder.

What are the basics of major depression? ›

Symptoms of depression include:
  • Ongoing sad, anxious or empty feelings.
  • A loss of interest in activities that normally are pleasurable, including sex.
  • Appetite and weight changes (either loss or gain)
  • Sleep problems (insomnia, early morning wakening or oversleeping)
  • Irritability.

What age has the most depression? ›

The average age of onset for major depressive disorder is between 35 and 40 years of age. Onset in early adulthood may be linked with more depressive episodes, a longer duration of illness, and therefore a more difficult clinical course.

What are three causes and effects of depression? ›

Stress, unhealthy diet, and limited exercise are all common parts of being depressed that might contribute to heart problems in the future. Sleep issues. Sleep changes are extremely common among depressed individuals and can include both insomnia and over-sleeping.

What are the 3 stages of depression? ›

Stages of depression: denial, diagnosis, and recovery.

What are 3 signs of clinical depression? ›

The psychological symptoms of depression include:
  • continuous low mood or sadness.
  • feeling hopeless and helpless.
  • having low self-esteem.
  • feeling tearful.
  • feeling guilt-ridden.
  • feeling irritable and intolerant of others.
  • having no motivation or interest in things.
  • finding it difficult to make decisions.

Is there a way to end depression? ›

Along with therapy and sometimes medication, there's a lot you can do on your own to fight back. Changing your behavior -- your physical activity, lifestyle, and even your way of thinking -- are all natural depression treatments.

What are the 2 main criteria for depression? ›

- Must have either depressed mood or loss of interest or pleasure. - Symptoms must cause significant distress or impairment. - No manic or hypomanic behavior.

What is the easiest way to explain depression? ›

Depression is a constant feeling of sadness and loss of interest, which stops you doing your normal activities. Different types of depression exist, with symptoms ranging from relatively minor to severe. Generally, depression does not result from a single event, but from a mix of events and factors.


1. 4 Reasons Highly Intelligent People Tend To Be Depressed
2. 10 Things Only Depressed People Will Understand
3. The Science of Depression
4. Harvard Psychiatrist Reveals the #1 Cause of Anxiety & Depression
(Thomas DeLauer)
5. What is depression? - Helen M. Farrell
6. Why Do You Feel More Depressed At Night?


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